Its main application is UV-light illumination of protein samples and excite intrinsic tryptophane fluorescence. In protein crystallography it provides a quick way to distinguish salt from protein crystals on the spot.
UV-Light Source as desktop microscope upgrade
XtalLight 100 can be used in combination with a variety of standard laboratory microscopes providing an additional UV-light illumination of a sample. The UV light is led onto the sample using a light guide, bypassing microscope optics. Different lengths of the light guides provide flexibility in the arrangement of the devices allowing installations within confined spaces.
Karsten Dierks, Arne Meyer, Howard Einspahr and Christian Betzel
Dynamic Light Scattering in Protein Crystallization Droplets: Adaptations for Analysis and Optimization of Crystallization Processes, Cryst. Growth Des., 2008, 8 (5), pp 1628–1634
Dominik Oberthuer, Emilio Melero-García, Karsten Dierks, Arne Meyer, Christian Betzel, Alfonso Garcia-Caballero and Jose A. Gavira
Monitoring and Scoring Counter-Diffusion Protein Crystallization Experiments in Capillaries by in situ Dynamic Light Scattering,
PLoS ONE 7(6): e33545. doi:10.1371/journal.pone.0033545
Arne Meyer, Karsten Dierks, Rana Hussein, Karl Brillet, Hevila Brognaro, and Christian Betzel
Systematic analysis of protein-detergent complexes applying dynamic light scattering to optimize solutions for crystallization trials,
Acta Crystallogr F Struct Biol Commun. 2015 Jan 1; 71(Pt 1): 75–81